IRT for Clinical Trials: Top Vendors 2018

Interactive Response Technology (IRT) helps clinical trials run smoothly by managing patient randomization and trial drug supply chain.

IRT is the umbrella term for the technology that clinical trial sites use to manage patient enrollment and randomization, whether through an Interactive Web Response System (IWRS) or Interactive Voice Response System (IVRS). As the names imply, IWRS allows users to enter patient information and dosing over the web, while IVRS, the older type of system, uses phone and voice to enter information.

IVRS technology in particular has been in use for several decades now, but IRT for clinical trials continue to evolve as study needs change, too. For example, more systems now include patient engagement functionality as trials focus more on patient centricity. As sponsors become more flexible and responsive in terms of study protocol, supply chain needs have changed with them. Today's IRT allows clinical trial sites to adjust to changes and stay on top of supplies every step of the way.

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IRT for Patient Engagement

When evaluating IRT vendors, one useful, newer feature is built-in patient engagement. Because IRT systems allow studies to remain blinded, their patient engagement features allow you to send reminders to patients with blinded information, as well. Your messaging can be specific to the patient's treatment arm without compromising the study.

In addition to sharing reminders about upcoming study visits, with some IRT, you can set up newsletters and other engaging content as well right from the system.

IRT and Supply Chain Management

Drug supply chain management has always been a critical part of IRT, but newer systems include more advanced monitoring and even predictive supply ordering. 

Predictive algorithms track factors like subject discontinuation to maintain the right drug supplies without ordering too much. Some companies also offer apps to help you track supplies on the go and receive alerts about shipping disruptions or temperature changes in your drug supply.

 Choosing an IRT Vendor

Below, you'll find a chart listing the most prominent IRT suppliers and the top features of each of their tools. To get a sense of whether the company is the right fit for your site or trial, these questions may be helpful for starting the conversation:

  • What are your timelines like for configuring your system to a new trial? (It may be helpful to share your study's protocol with the vendor at this time so they can give a more accurate answer)
  • What other systems can your tool communicate with?
  • What reporting features does your system include?
  • How can I engage patients using your system?
  • Does your system include an app, or is it mobile friendly?
  • What support services do you offer?
  IRT for Clinical Trials: Top Vendors 2018
 Clinitec              
  • Cloud-based, mobile-friendly platform
  • Out-of-the-box deployment
  • Subject enrollment tracking
  • Randomization features
  • Supply chain management
  • Integration with third party EDC, CTMS, eCOA and other systems
 ITclinical     
  • Randomize patients and track their progress in real-time
  • Supply chain management, including the location of your supply
  • Include your study’s custom randomization algorithm
  • Receive email notifications when subjects enroll
 Medpace  
  • Real-time volunteer enrollment tracking
  • Randomize patients into your trial
  • Supply chain management
  • Integration with central lab eligibility systems
 PPD  
  • Track volunteer enrollment
  • Randomize patients into your trial
  • Supply chain management
  • Reporting on current status, trends and projections
  • Global support desk is available 24/7
 Veracity Logic    
  • Track volunteer enrollment 
  • Randomize patients into your trial
  • Supply chain management
  • Shipping and inventory control
  • Integration with EDC, CTMS and ePRO systems
  • Predictive resupply for trial drugs
 YPrime  
  • Track volunteer enrollment 
  • Randomize patients into your trial 
  • Manage your drug supply chain from shipment to arrival 
  • All of your technology can be on a single platform if you use the company’s eCOA