ePRO Vendors: Comparison of Top Companies

Electronic patient reported outcomes (ePRO) are a growing way for clinical studies to collect meaningful patient data easily. With ePRO, patients record symptoms, side effects, and other data points on their own device with ePRO software installed, or on a device provided by the study.

The right ePRO solutions work for your study and for patients, too, whether you're looking for helpful reminder features or bring-your-own-device capabilities so patients can use devices they're comfortable with.

It's also important to look for a system that communicates easily with your existing Interactive Web Response System (IWRS), Randomization and Trial Supply Management (RTSM) technology, and any other tools your trial will be using.

We've highlighted the top ePRO vendors and their key features to help you make a decision and start collecting valuable patient data.

Download our free clinical trial recruitment plan template.


 Comparison of ePRO Vendors

Vendor  Features                                               
  • Tools for patient engagement, including newsletters, games, and email alerts
  • Easy data capture such as medication usage, diagrams and scales, and daily events including exercise, mood, medical episode, etc.
  • Delivery on a 7" or 10" tablet; the device is part of the system
  • Bring-your-own device compatible
  • Real-time reporting
  • Automated alerts to patients
  • Bring-your-own-device compatible
  • iOS and Android platform
  • Easy integration with Electronic Data Capture (EDC) Clinical Trial Management System (CTMS), and Interactive Response Technology (IRT) vendors 
Castor ePRO
  • Quick survey creation using 20+ field types, pre-built templates, and validations
  • Survey participant management through bulk invites, automatic triggers, and a dynamic dashboard
  • Complete record-level overview within a single platform
Crucial Data Solutions                                    
  • Bring-your-own-device compatible
  • Available on all platforms: web or downloadable mobile apps for iOS or Android
  • Automated alerts to patients and researchers
 CRF Health             
  • Drag and drop tools to easily collaborate with stakeholders during design
  • Easy screenshot generation to share for IRB approval
  • Bring-your-own-device compatible, or use a CRF device
  • Bring-your-own-device compatible
  • Mental health screening tools
  • Easy integration with clinical trial technology
  • Near real-time reporting tools
  • Bring-your-own-device compatible
  • Patient engagement app for keeping patients informed on the trial
  • Tablets and smartphones also available
  • Easy configuration with no custom development
  • Compatible with iOS and Android
  • Compatible with wearable devices
  • Broad self-reported patient data capture ranging from diaries to complex clinical assessments, such as a depression evaluation
  • Easy integration with EDC, IVR, and CTMS technologies from Parexel as well as other vendors
  • 24/7 desk support


ePRO Vendors: What to expect during the sales process

Once you've identified which ePRO vendors you're interested in working with, most will put together a prototype of an eDiary based on your protocol during the sales process. Your study's protocol doesn't need to be completely finalized during this stage, but the more final it is, the better of an idea you'll get of what the vendor can provide for your study.

Vendors also advise writing your protocol with an eDiary solution in mind, rather than using language based on traditional paper diaries.

After you've finalized your chosen vendor, they will most likely set up a kickoff meeting to learn more about your needs and start designing your ePRO solution. Some companies offer more of a DIY set-up, so that's one feature to factor in when making your decisions based on staff skillsets and availability.

After your new ePRO system is set up and you're ready to start finding the right patients, Antidote can help. Download our case studies to read about how we've accelerated research for sponsors across a range of conditions.